The paper contains the analysis of the goals and objectives of improving energy efficiency of residential buildings, as well as the methodology of selecting energy-efficient modernization measures for historic buildings.The priority objective of this study was selected as a residential housing energy efficiency of historic buildings as a tool to im
Cystic fibrosis (CF) is a lethal autosomal recessive genetic disease caused by mutations Ketchup in the CF transmembrane conductance regulator (CFTR).Mutations in the CFTR gene may result in a defective processing of its protein and alter the function and regulation of this channel.Mutations are associated with different symptoms, including pancrea
Small GTPases of the Rab family not only regulate target recognition in membrane traffic but also control other cellular functions such as cytoskeletal transport and autophagy.Here we show that Rab26 is specifically associated with clusters of synaptic vesicles in neurites.Overexpression of active but not of GDP-preferring Rab26 enhances vesicle cl